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1,4 Dioxane

CAS : 123-91-1

1,4 Dioxane


1, 4-Dioxane is a colorless, highly flammable hygroscopic liquid with a mild, sweet ether-like odor. It is infinitely soluble in water and most organic solvents (i.e., alcohol, ether, acetone, benzene, acetic acid). It is also miscible with aromatic hydrocarbons and oils. 1, 4-Dioxane is stable, incompatible with oxidizing agents, oxygen, halogens, reducing agents, moisture.

1,4 Dioxane


Color (APHA) Less than 5
Density (20°C) (g/cm3) 1.033
Water Content (%) 0.01
Acidity (as Acetic Acid) (%) Less than 0.001
Initial Point (°C) 101.5
Dry Point (°C) 102.5
Freezing Point (°C) 11.8
Purity (%) More than 99.95




1, 4-Dioxane is used primarily as a solvent in paints, varnishes, lacquers, cosmetics, deodorants, cleaning and detergent preparations, and in liquid scintillation counting mediums. There is also the potential for use it as a solvent in the processing of crude petroleum, petroleum refining, petrochemicals, pulp and paper, explosives, commercial printing, electroplating/polishing, pesticides, dyes, fibers, pharmaceuticals, veterinary drugs, adhesives, semiconductors, electronic components, photographic equipment, magnetic recording media, polymers, plastics, rubber manufacture, organic and inorganic chemical manufacture.

In the laboratory, 1, 4-dioxane is useful as a cryoscopy solvent for molecular mass determinations and as a stable reaction medium solvent in chemical synthesis, research and analysis. Because of its lower toxicity, it is sometimes substituted with tetrahydrofuran (THF) in some processes


1, 4-Dioxane often has been used with chlorinated solvents or volatile organic compounds (VOCs). It is primarily used as a stabilizer and corrosion inhibitor for 1, 1, 1-trichloroethane for storage and transport in aluminum containers.


1, 4-Dioxane is also used as a wetting and dispersing agent in textile processing

Other uses: 

·      Preparation of histological sections for microscopic examination.

·      Extracting agent.

·      Analytical reagent for the laboratory use



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