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Thiophenol

CAS # 108-98-5

DESCRIPTION

Thiophenol is an organosulfur compound with the formula C6H5SH, sometimes abbreviated as PhSH. This foul-smelling colorless liquid is the simplest aromatic thiol. The chemical structures of thiophenol and its derivatives are analogous to phenols except the oxygen atom in the hydroxyl group (-OH) bonded to the aromatic ring is replaced by a sulfur atom. The prefix thio- implies a sulfur-containing compound and when used before a root word name for a compound which would normally contain an oxygen atom, in the case of 'thiol' that the alcohol oxygen atom is replaced by a sulfur atom.

 

PROPERTIES

Appearance

Colorless liquid

Odor

Unpleasant, pungent

Density

1.0766 g/mL

Melting point

−15 °C (5 °F; 258 K)

Boiling point

169 °C (336 °F; 442 K)

Solubility in water

0.08%[2]

Solubility

Most organic solvents; aqueous base

Vapor pressure

1 mmHg (18°C)[2]

Acidity (pKa)

6.62 (H2O)

10.28 (DMSO)

Magnetic susceptibility (χ)

-70.8·10−6 cm3/mol


APPLICATION

Thiophenols are used in the production of pharmaceuticals including of sulfonamides. The antifungal agents butoconazole and merthiolate are derivatives of thiophenols.


PACKAGING OPTIONS

Drums