Thiophenol
CAS # 108-98-5
DESCRIPTION
Thiophenol is an organosulfur compound with the formula C6H5SH, sometimes abbreviated as PhSH. This foul-smelling colorless liquid is the simplest aromatic thiol. The chemical structures of thiophenol and its derivatives are analogous to phenols except the oxygen atom in the hydroxyl group (-OH) bonded to the aromatic ring is replaced by a sulfur atom. The prefix thio- implies a sulfur-containing compound and when used before a root word name for a compound which would normally contain an oxygen atom, in the case of 'thiol' that the alcohol oxygen atom is replaced by a sulfur atom.
PROPERTIES
|
Appearance |
Colorless liquid |
|
Odor |
Unpleasant, pungent |
|
Density |
1.0766 g/mL |
|
Melting point |
−15 °C (5 °F; 258 K) |
|
Boiling point |
169 °C (336 °F; 442 K) |
|
Solubility in water |
0.08%[2] |
|
Solubility |
Most organic solvents; aqueous base |
|
Vapor pressure |
1 mmHg (18°C)[2] |
|
Acidity (pKa) |
6.62 (H2O) 10.28 (DMSO) |
|
Magnetic susceptibility (χ) |
-70.8·10−6 cm3/mol |
APPLICATION
Thiophenols are used in the production of
pharmaceuticals including of sulfonamides. The antifungal agents butoconazole
and merthiolate are derivatives of thiophenols.
PACKAGING OPTIONS
Drums